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November 30, 2023The Role of Genetic Testing in Psychiatric Medication Management

What is Genetic Testing?
Genetic testing for psychiatric medication, also known as pharmacogenetic testing, offers a personalized approach to medication management by analyzing a patient's DNA to predict how they may respond to different psychiatric medications. This can help reduce the guesswork in prescribing, leading to more effective and efficient treatment
How Does Genetic Testing Work?
Genetic testing for psychiatric medications involves a simple cheek swab that is analyzed for genetic markers related to drug metabolism. These markers can indicate:
- How quickly or slowly a person metabolizes certain medications (which affects dosage recommendations).
- Whether a person is at increased risk for side effects with specific drugs.
- Which medications may be more or less effective based on their genetic profile.
The results help your provider make informed decisions about which medications are likely to work best for a patient, potentially reducing the trial-and-error period that often comes with medication management.
Benefits of DNA Testing for Antidepressants and Other Psychiatric Medications
- Personalized Medication Management - Genetic testing allows for a tailored approach to psychiatric medication management, taking into account an individual's unique genetic makeup rather than relying on generalized treatment guidelines.
- Faster Relief from Symptoms - By identifying medications that are more likely to be effective, patients may experience relief sooner, rather than spending months trying different prescriptions.
- Reduced Risk of Side Effects - Certain genetic markers can indicate a higher likelihood of side effects with specific medications. Knowing the information in advance can help providers choose options that minimize adverse reactions.
- Better Adherence to Treatment - When patients experience fewer side effects and see quicker improvements, they are more likely to adhere to their prescribed treatment plan, improving mental health outcomes.
- Guidance for Medication Adjustments - Genetic testing can help determine if a patient needs a higher or lower dose of a medication based on how their body metabolizes it, allowing for more precise dosing recommendations.
Who Should Consider Genetic Testing for Psychiatric Medications?
Genetic testing may be especially helpful for individuals who:
- Have tried multiple antidepressants or other psychiatric medications without success.
- Experience severe or unusual side effects from medications.
- Are starting considering antidepressants or other psychiatric medications for the first time and want a more personalized approach.
- Have a family history of medication resistant depression, psychiatric medication resistance or sensitivity.

Limitations of Genetic Testing in Psychiatry
While genetic testing is a valuable tool, it is not a standalone solution. It does not provide absolute answers, but rather guidance on which medications may be more suitable based on genetic factors. Other factors, such as lifestyle, medical history, and environmental influences, also play a role in medication response.
Additionally, not all insurance plans cover genetic testing for psychiatric medications, so patients should check with their provider about potential costs.
Where Can I Find Genetic Testing for Psychiatric Medications?
If you are looking for genetic testing for psychiatric medications in Oregon, NeuStart Psychiatry & TMS offers this service with locations in Portland and in Salem. Our experienced providers use genetic testing to create personalized treatment plans, ensuring you receive the most effective medication with the fewest side effects.
To learn more about how genetic testing can support your mental health journey or to schedule an appointment, contact us today. Let's take the guesswork out of medication management and find a treatment plan that works best for you.